Manchester City handed Chelsea only their second Women's Super League defeat of the season to draw level on points with Manchester United at the top of the table.
First-half finishes from Filippa Angeldahl and Lauren Hemp earned a well-deserved 2-0 victory for City as the defending champions offered little in front of goal.
Emma Hayes doubts there is much to learn from Arsenal's 5-1 demolition job of Lyon earlier this season ahead of Chelsea's clash with the European champions.
The Gunners laid down a marker in the Champions League last October with a stunning win over a club that have won the competition in six of the last seven seasons.
Holders Chelsea will face Aston Villa in the Women’s FA Cup semi-finals, while Manchester United are taking on Brighton.
The Blues beat Reading 3-1 to reach the final four of this year's competition and are looking to secure their third successive triumph.
Manchester United saw off the challenge of Championship side Lewes to reach the Women's FA Cup semi-finals.
Lewes were the lowest ranked side left in the competition and they went behind when Rhian Cleverly's own goal put the Women's Super League title challengers in front just eight minutes in.
Premier League title-chasers Arsenal dominated the London Football Awards with an impressive four winners.
Martin Odegaard picked up the Premier League Player of the Year for his integral role in helping the Gunners establish a five-point lead at the summit of the English top flight.
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